Yung-Chi Cheng, PhD
Henry Bronson Professor of Pharmacology; Director, Therapeutics/Chemotherapy Program; Chairman, Consortium for the Globalization of Chinese Medicine (CGCM)
Departments & Organizations
Biological and Biomedical Sciences (BBS): Microbiology | Molecular Medicine, Pharmacology, and Physiology | Biochemistry, Biophysics and Structural Biology: Cell Cycle and Signal Transduction; DNA Dynamics; Drug Design, Discovery and Mechanism
Stem Cell Center, Yale
Developmental Therapeutics
Pharmacology(
Liver Center)
Developmental Therapeutics
Molecular Virology
Research Interests
Cancer; Viral chemotherapy more...
Education
- Ph.D., Brown University, 1972
Selected Publications
- Hsu, C., et al. (2007). Comparison of phosphorylation of 4?f-Ethynyl 2?f, 3?f-dihydro-3?f-deoxythymidine with other anti-HIV Thymidine analogs. Antimicrob. Agents Chemother. 51 May.
- Lam, W., Park, S.-Y., Leung, C.-H., and Cheng, Y.-C. (2006). Apurinic?/?apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (Troxacitabine and beta-L-2?f,3?f-Dideoxy- 2?f,3?f-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and beta-D-arabinofuranosylcytosine). Molec. Pharm. 69(5):1607-1614.
