Sidi Chen, PhD

Assistant Professor

Departments & Organizations

Genetics: Sidi Chen Lab

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology: B and T Cell Effector and Memory Cell Differentiation; Computational Immunology; Consequences of an Immune Response; Mounting an Immune Response | Molecular Cell Biology, Genetics and Development: Evolutionary Biology; Genetics and Genomics; Human Disease; Quantitative/Systems Biology; Regenerative Biology /Stem Cells; RNA Biology

Yale Cancer Center: Genomics, Genetics, and Epigenetics

Faculty Research


I earned my PhD from The University of Chicago, and performed postdoctoral studies at MIT and the Broad Institute. My current research focuses on cancer systems biology, in particular in vivo CRISPR/Cas9-mediated cancer modeling and genetic screening. I have led studies on essential function of new genes in animal development and tumorigenesis, microRNA regulation of tumor hypoxia and angiogenesis, in vivo modeling of lung cancer and liver cancer using gene editing, and genome-wide screens for metastasis regulators.

Education & Training

PhD The University of Chicago (2011)
Visiting Postdoc Broad Institute of MIT and Harvard
Postdoctoral Fellow MIT
Visiting Student Stanford University

Honors & Recognition

  • AACR NextGen Award for Transformative Cancer ResearchAACR (2017)

  • LCRP Idea Development AwardDepartment of Defense (2017)

  • Exceptional Research Grant AwardBreast Cancer Alliance (2017)

  • St. Baldrick’s Foundation Award (2016)

  • Young Investigator AwardMelanoma Research Alliance (2016)

  • Dale Frey Award for Breakthrough ScientistsDamon Runyon Cancer Research Foundation (2015)

  • Damon Runyon Cancer Research FellowshipDamon Runyon Cancer Research Foundation (2012)

  • Best Dissertation AwardThe University of Chicago (2011)

  • Chair’s Special Award, Best PresentationGordon Research Conference (2011)

  • National Science Foundation Doctoral Dissertation Improvement Grant National Science Foundation (2010)

  • Chun-Tsung ScholarTsung-Dao Lee Foundation (2002)

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Contact Info

Sidi Chen, PhD
Lab Location
Sidi Chen LaboratoryWest Campus Integrative Science & Technology Center
850 West Campus Drive, Rm 314

West Haven, CT 06516
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Mailing Address
850 West Campus Drive
Integrated Science & Technology Center

West Haven, CT 06516

Curriculum Vitae

Chen Lab website