Richard Kibbey, MD/PhD

Dr. Kibbey obtained his undergraduate degrees in music (B.A.) and an honors degree in biochemistry (B.S.) at Trinity University in San Antonio in 1991. He then obtained his combined M.D. and Ph.D. at the University of Texas Southwestern Medical School in 2000. His Ph.D. was in Cellular and Molecular Biophysics and involved determining the NMR structure of peptides from the LDL receptor under his mentors Drs. R.G.W. Anderson and L. Gierasch. Subsequently, he went to Yale University in where he was selected for the ABIM short-track in Categorical Internal Medicine. In 2002 he stayed on for his Endocrinology fellowship at Yale and is now board certified in Internal Medicine and Endocrinology. While in his fellowship he worked in the laboratory of Dr. Gerald Shulman on metabolism in the pathophysiology of Type-2 Diabetes Mellitus. Here he identified mitochondrial GTP as a metabolic signal in the mitochondria sensing flux in the pancreatic beta-cell as a crucial component of the signal to secrete insulin. His laboratory also has developed a novel platform using stable isotopes and mass spectrometry named Mass Isotopomer MultiOrdinate Spectral Analysis (MIMOSA) that measures the flow of metabolism inside and between tissues. He is now an Associate Professor in the Departments of Internal Medicine/Endocrinology and Cellular & Molecular Physiology. He continues to see patients at Yale Health and has an independent NIH-supported laboratory doing research on islet and whole body physiology in order to understand/prevent/treat Type-2 diabetes.