Richard Bucala, MD, PhD

Professor of Medicine (Rheumatology), of Epidemiology (Microbial Diseases) and of Pathology and Residential College Associate Fellow in Faculty of Arts and Sciences

Departments & Organizations

Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology

Yale Medical Group

Cancer Immunology

Global Health Initiative: Infectious Diseases

School of Public Health: Parasitology Program

Pathology

Internal Medicine: Rheumatology | Diabetes Endocrinology Research Center


Research Interests

Mechanisms by which host immunity converts from a protective response to one producing disease and tissue pathology; Emergence of steroid resistance; Biochemical, biological, and genetic characterization of cytokine MIF; MIF's role in malaria; Role of fibrocytes in different systemic fibroses more...


Education

  • B.S., Yale University, 1979
  • M.S., Yale University, 1979
  • Ph.D., Rockefeller University, 1985
  • M.D., Cornell College, 1986

Selected Publications

  • Leng L, Chen L, Fan J, Greven D, Arjona A, Du X, Austin D, Kashgarian M, Yin Z, Huang XR, Lan HY, Lolis E, Nikolic-Paterson D, Bucala R. 2011. A small-molecule MIF antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice. J Immunol. 186, 527-538.
  • Jorgensen WL, Gandavadi S, Du X, Hare AA, Trofimov A, Leng L, Bucala R. 2010. Receptor agonists of macrophage migration inhibitory factor. Bioorg Med Chem Lett. 20, 7033-7036.
  • Awandare GA, Martinson JJ, Were T, Ouma C, Davenport GC, Ong'echa JM, Wang W, Leng L, Ferrell RE, Bucala R, Perkins DJ. 2009. MIF Promoter Polymorphisms and Susceptibility to Severe Malarial Anemia. J Infect Dis. 15: 629-637.

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