Gerald S Shadel, PhD

Professor of Pathology and of Genetics; Director, Pathology Research

Departments & Organizations


Genomics, Genetics, and Epigenetics

Integrative Cell Signaling & Neurobiology of Metabolism (ICSNM)

Office of Student Research

Pathology: ExPath | Pathology Research | Shadel Lab

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Human Disease; Nucleic Acids; Oncogenes, Tumor Suppressor Genes, and Cell Cycle Control; Receptors and Signal Transduction | Molecular Medicine, Pharmacology, and Physiology: Cancer Biology and Therapeutics; Genetics, Genomics and Proteomics; Human Disease Pathology, Physiology and Intervention; Metabolism; Receptors and Signal Transduction


Gerald S. Shadel received a B.S. from the University of Nevada, Las Vegas in 1986 and his Ph.D. from Texas A&M University in 1991. He went on to Stanford University, where he was a Damon-Runyon postdoctoral fellow and studied the mechanism of mitochondrial gene expression. As an Assistant/Associate Professor of Biochemistry at Emory University from 1997-2004, he continued research in this area using biochemical methods and yeast and tissue culture models. He is currently a Professor of Pathology and Genetics at Yale University, where he studies the role of mitochondria in human disease and aging, now also using mouse models. In 2007, Dr. Shadel received the Amgen Outstanding Investigator Award from ASIP recognizing his contributions in this important area of research and medicine.

Education & Training

PhD Texas A & M University (1991)
BS University of Nevada, Las Vegas, Chemistry (1986)
Postdoctoral Fellow Stanford University

Honors & Recognition

  • Glenn Award for Research in Biological Mechanisms of AgingGlenn Foundation (2011)

  • Amgen Outstanding Investigator AwardAmerican Society for Investigative Pathology (2007)

Professional Service

  • Director of Graduate Studies Experimental Pathology Graduate Program (2009 - 2012)

  • Term Appointments and Promotions Committee (2008 - 2011)

  • CMAD Study Section NIH

  • member American Association for the Advancement of Science (AAAS)

  • member American Society for Biochemistry and Molecular Biology (ASBMB)

  • member American Society for Investigative Pathology (ASIP)

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