Eric RF Meffre, PhD
Associate Professor of Immunobiology and of Medicine (Immunology)
Departments & Organizations
Biological and Biomedical Sciences (BBS): Immunology
Cancer Immunology
Immunobiology
Internal Medicine: Allergy & Clinical Immunology
Research Interests
Human B cell tolerance; primary immunodeficiencies; autoimmune disease more...
Education
- B.S., University of Paris, 1988
- M.S., University of Paris, 1989
- Ph.D., University of Aix-Marseille, France, 1996
Selected Publications
- L. Ménard, D. Saadoun, I. Isnardi, Y.-S. Ng, G. Meyers, C. Massad, C. Price, C. Abraham, R. Motaghedi, J. H. Buckner, P. K. Gregersen and E. Meffre. The PTPN22 risk allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. 2011. J. Clin. Invest. 121: 3635-44.
- G. Meyers, Y.-S. Ng, J. M. Bannock, A. Lavoie, J. E. Walter, L. D. Notarangelo, S. S. Kilic, G. Aksu, M. Debré, F. Rieux-Laucat, M. E. Conley, C. Cunningham-Rundles, A. Durandy and E. Meffre. Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans. 2011. Proc. Natl. Acad. Sci. USA. 108:11554-9.
- L. Ménard, J. Samuels, Y.-S. Ng and E. Meffre. Inflammation-independent defective early B cell tolerance checkpoints in rheumatoid arthritis. 2011. Arthritis Rheum. 63:1237-45.
