Elias Lolis, PhD
Professor of Pharmacology; Director of Graduate Studies
Departments & Organizations
Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Molecular Medicine, Pharmacology, and Physiology | Biochemistry, Biophysics and Structural Biology: Cell Cycle and Signal Transduction; Membrane Biology and Motion; crystallography, NMR, mass spectrometry, cryo-electron...faculty
Developmental Therapeutics
Structural Biology
Pharmacology
Developmental Therapeutics
Research Interests
Cancer; Inflammation; Infectious disease; macromolecular X-ray crystallography; Signaling pathways; Drug Design; High throughput screening (HTPS) more...
Education
- B.A., Columbia College, 1984
- Ph.D., Massachusetts Institute of Technology, 1989
Selected Publications
- Cho Y, Vermeire JJ, Merkel JS, Leng L, Du X, Bucala R, Cappello M, Lolis E. Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem Biol. 2011 Sep 23;18(9):1089-101.
- Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. Epub 2010 Jun 8.
- Murphy JW, Yuan H, Kong Y, Xiong Y, Lolis EJ. Heterologous quaternary structure of CXCL12 and its relationship to the CC chemokine family. Proteins. 2010 Apr;78(5):1331-7
