Biochemistry, Quantitative Biology, Biophysics and Structural Biology

The Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS) Track provides students with experimental, theoretical, and computational research training across a broad range of scales, from molecules to cells to whole organisms. Our approaches encompass a full range of modern disciplines including biochemistry and molecular biology, biophysics, chemistry, cell biology, genomics and proteomics, computational biology, and structural biology.

Recent revolutionary developments in modern biology have greatly advanced the diverse interests of our faculty. Technical advances in X-ray crystallography, cryo-electron microscopy (cryo-EM), live imaging, single molecule studies, next-generation sequencing, and mass spectrometry have led to a wealth of quantitative data for addressing long-standing biology questions. The integration of experimental data with computer modeling has stimulated productive collaborations among the disciplines of biology, chemistry, physics, and engineering. Our students will thus have a broad training in experimental and quantitative skills to perform in-depth mechanistic studies of diverse biological processes.

Students in this Track are expected to meet rigorous standards in their course work and research. Our mission is to impart the intellectual and practical skills needed to engage in biological research at the highest level. We believe this requires a combination of deep understanding of biology and chemistry and the application of quantitative methods and modeling. It is our goal to develop our students’ independence, creativity and rigor, while fostering their adventurousness. These are the attributes that will propel our trainees to be future leaders in their field.

    "The BBSB track provides a well rounded foundation in biochemistry and biophysics through its core courses, while electives allow students to develop their own passions. Laboratory research rotations allow students to experience a range of research topics and mentors before choosing a thesis lab, experiencing classroom knowledge first hand. The BBSB track has been a perfect fit for my existing interest in structural biology. I have found a rich community of scholars in departmental seminars, informal research talks and in daily conversations with fellow students. During my free time, New Haven provides endless opportunities for exploration." 
    Sarah Smaga 
    Biochemistry, Biophysics and Structural Biology Track

    Photo Courtesy of Hyungmee Lim